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Everything is about to change on  Grey's Anatomy Season 12 . Actually, correction: According to Meredith in the first promo for new fall episodes, everything has already changed. The 21-second teaser gives us a look at Meredith lying alone in bed (Rest in Peace, Derek Shepherd), along with some demolition work taking place in her house and some enthusiastic high-fives taking place at work. Oh, and someone gets punched in the face in the hospital. That also happens here Creator Shonda Rhimes has promised a “lighter tone” for the series this fall, though the question still remains: Will people tune in now that Patrick Dempsey is gone? Or will they continue to hold his character's death, and the way it was handled, against the long-running drama? Check out fresh footage now and tune in for Grey's Anatomy Season 12 Episode 1 on Thursday, September 24 at 8/7c.

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Grey’s Anatomy Season 12 Trailer: Everything Has Changed