In the upcoming dramedy 50/50 , 27-year-old Adam (Joseph Gordon-Levitt) finds out he has a cancerous tumor growing in his back, and proceeds to tell his best friend Kyle (Seth Rogen) outside a coffee shop. If only it happened like that in reality. 50/50 is based on the life of screenwriter Will Reiser, and when he called Rogen, his best friend, to tell him the bad news, the Knocked Up star was in a compromising situation: mid-poop. Click through to watch Rogen explain.
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VIDEO: Seth Rogen Was Told His Best Friend Had Cancer While on the Toilet
